HPE 815100-B21 – ProLiant DL380 Gen10 Server

HPE 815100-B21 ProLiant DL380 Gen10 Server

Overview

The HPE 815100-B21 ProLiant DL380 Gen10 is a dual-socket enterprise rack server designed for virtualization, database processing, software-defined storage, and mixed workload data center environments. It provides scalable compute infrastructure for organizations requiring flexible expansion, memory scalability, and enterprise reliability in a standard rack platform.

The system supports Intel Xeon Scalable processors, DDR4 SmartMemory, and multiple storage configurations including SAS, SATA, and NVMe drives. Integrated security technologies, redundant power architecture, and flexible PCIe expansion make it suitable for production workloads requiring uptime and long-term infrastructure scalability.

Its 2U rack form factor fits enterprise data centers, colocation environments, branch infrastructure, and private cloud deployments where balanced compute density and storage flexibility are operational requirements. The platform supports both performance-focused and capacity-focused deployment models depending on storage and processor configuration.

The server integrates with HPE OneView and iLO management ecosystems and supports VMware, Microsoft, Linux, and hybrid cloud infrastructure deployments.

Typical Deployment Scenarios

• VMware and Hyper-V virtualization clusters
• Enterprise database hosting infrastructure
• Software-defined storage deployments
• Hybrid cloud compute environments
• Mission-critical business applications
• Private cloud and VDI platforms

Technical Specifications

Compatibility / Ecosystem

The HPE 815100-B21 integrates with HPE OneView, HPE iLO 5, and enterprise ProLiant server environments. It supports VMware vSphere, Microsoft Hyper-V, Red Hat Enterprise Linux, SUSE Linux Enterprise Server, and Windows Server operating systems. The platform is compatible with HPE Smart Array controllers, HPE networking adapters, NVMe storage devices, and enterprise rack infrastructure deployments.